| Movie | The 78th Annual Drama League Awards | Herself - Host | 2012-05-18 |
| Movie | The 63rd Annual Tony Awards | Herself - Performer & Nominated: Best Leading Actress in a Musical | 2009-06-07 |
| Movie | The Matthew Shepard Story | Judy Shepard | 2006-06-04 |
| Series | Out of Practice | Dr. Lydia Barnes | 2005-09-01 |
| Movie | Christmas in Rockefeller Center | Herself | 2003-12-03 |
| Movie | A Girl Thing | Dr. Beth Noonan | 2001-01-20 |
| Movie | Isn't She Great | Florence Maybelle | 2000-01-28 |
| Movie | Hollywood Salutes Jodie Foster: An American Cinematheque Tribute | Herself | 1999 |
| Movie | Twilight | Lt. Verna Hollander | 1998-03-06 |
| Movie | Practical Magic | Aunt Frances | 1998-10-16 |
| Movie | Up Close & Personal | Marcia McGrath | 1996-03-01 |
| Movie | The 18th Annual CableACE Awards | Herself - Presenter | 1996-11-16 |
| Movie | The Prosecutors | Ingrid Maynard | 1996-12-02 |
| Movie | The 5th Annual GLAAD Media Awards | Herself | 1994-03-19 |
| Movie | The 20th Annual People's Choice Awards | Herself - Presenter: Favorite Actress in a Comedy Motion Picture | 1994 |
| Movie | Six Degrees of Separation | Ouisa | 1993-12-08 |
| Movie | The 40th Annual Tony Awards | Herself - Nominee: Best Featured Actress in a Play | 1986 |
| Series | The Stockard Channing Show | Susan Goodenow | 1980-03-24 |
| Series | Stockard Channing in Just Friends | Susan Hughes | 1979-03-04 |
| Movie | Grease | Rizzo | 1978-06-16 |
| Movie | The Big Bus | Kitty Baxter | 1976-10-22 |