Fast-talking and feisty-looking John Leguizamo has continued to impress movie audiences with his versatility: he can play sensitive and naïve young men, such as Johnny in Hangin' with the Homeboys (1991); cold-blooded killers like Benny Blanco in Carlito's Way (1993); a heroic Navy SEAL, stopping aerial terrorists in Executive Decision (1996); and ...
Nominated for 1 Golden Globe. Another 10 wins & 18 nominations.
| Movie | Last of the Showmen | Unknown | 2017 |
| Series | Taxi 22 | Unknown | 2017 |
| Movie | The Adventures of Drunky | Unknown | 2017 |
| Movie | The Godmother | None | 2017 |
| Movie | Tlatelolco68 | Unknown | 2017 |
| Movie | 11:55 | Unknown | 2016 |
| Movie | John Wick: Chapter Two | Unknown | 2016 |
| Movie | The Hollow Point | Unknown | 2016 |
| Movie | Michael Jackson's Journey from Motown to Off the Wall | Unknown | 2016 |
| Movie | Jekyll Island | Unknown | 2016 |
| Movie | The Infiltrator | Emir Abreu | 2016-08-31 |
| Series | The Meredith Vieira Show | Unknown | 2016-03-05 |
| Movie | Kings of Van Nuys | Del Trotter | 2016-03-08 |
| Movie | The Quest for the Titan | Himself / Gune | 2016-02-12 |
| Movie | El Patron | Pablo Escobar | 2016-02-12 |
| Movie | Ice Age: Collision Course | Unknown | 2016-07-22 |
| Movie | Stealing Cars | Montgomery De La Cruz | 2016-04-05 |
| Movie | Sisters | Dave | 2015-12-18 |
| Movie | Cymbeline | Pisanio | 2015-03-13 |
| Series | Let's Go, DFW! | Unknown | 2015-08-22 |
| Movie | Get Squirrely | Unknown | 2015 |
| Movie | Experimenter | Unknown | 2015 |
| Series | The Adventures of Puss in Boots | Unknown | 2015 |
| Series | The Nightly Show with Larry Wilmore | Unknown | 2015-01-19 |
| Movie | Cosmic Scrat-tastrophe | Unknown | 2015 |
| Movie | American Ultra | Unknown | 2015 |
| Movie | The Latin Explosion: A New America | Himself - Narrator | 2015-11-16 |
| Series | Bloodline | Unknown | 2015 |
| Movie | Meadowland | Pete | 2015-04-17 |
| Movie | The 8th Annual CNN Heroes: An All-Star Tribute | Unknown | 2014 |
| Movie | Super Mario Bros: This Ain't No Video Game | Unknown | 2014 |
| Movie | John Leguizamo's Ghetto Klown | Unknown | 2014 |
| Movie | Ride Along | Santiago | 2014-01-17 |
| Movie | Fugly! | Unknown | 2014 |
| Series | Late Night with Seth Meyers | Unknown | 2014 |
| Series | The Lineup: Best New York Movies | Unknown | 2014 |
| Series | HuffPost Live Conversations | Unknown | 2014 |
| Movie | John Wick | Aurelio | 2014-10-24 |
| Movie | Chef | Unknown | 2014 |
| Series | Live with Kelly and Michael | Unknown | 2013 |
| Movie | Salsa Giants | Unknown | 2013 |
| Movie | The Counselor | Unknown | 2013 |
| Movie | Fish N Chips: The Movie | Unknown | 2013 |
| Movie | Walking with Dinosaurs 3D | Unknown | 2013 |
| Movie | Kick-Ass 2 | Unknown | 2013-08-16 |
| Series | The Big Interview with Dan Rather | Unknown | 2013 |
| Series | Sanjay and Craig | Unknown | 2013-05-25 |
| Series | The Arsenio Hall Show | Unknown | 2013-09-09 |
| Movie | Tales from a Ghetto Klown | Unknown | 2013 |
| Movie | Underdogs | Unknown | 2013 |
| Movie | King John | Unknown | 2013 |
| Movie | Ice Age Village | Unknown | 2013 |
| Series | Hola! La | Guest | 2012-09-30 |
| Movie | Ice Age: Continental Drift - Arctic Games | Sid | 2012-07-10 |
| Movie | One for the Money | Unknown | 2012 |
| Movie | Ice Age Continental Drift: Granny and the Stink of the Sloths | Unknown | 2012 |
| Movie | Inocente | Unknown | 2012 |
| Movie | The Mark Twain Prize: Ellen DeGeneres | Unknown | 2012 |
| Movie | The Standbys | Unknown | 2012 |
| Movie | The Trip 2 | Unknown | 2012 |
| Movie | Ice Age: Continental Drift | Unknown | 2012-07-13 |
| Series | A Poem Is... | Unknown | 2011 |
| Series | Good Day L.A. | Unknown | 2011 |
| Movie | Hollywood at Home | Unknown | 2011 |
| Series | Show People with Paul Wontorek | Unknown | 2011 |
| Movie | Scrat's Continental Crack-Up: Part 2 | Unknown | 2011 |
| Series | Talk Stoop with Cat Greenleaf | Unknown | 2011 |
| Movie | Ballplayer: Pelotero | Unknown | 2011 |
| Movie | Making the Case: Creating the Lincoln Lawyer | Unknown | 2011 |
| Movie | The Latino List | Unknown | 2011 |
| Movie | The 77th Annual Drama League Awards | Himself - Presenter | 2011-05-20 |
| Movie | The Lincoln Lawyer | Unknown | 2011-03-18 |
| Movie | The 65th Annual Tony Awards | Unknown | 2011-06-12 |
| Series | Big Morning Buzz Live with Nick Lachey | Unknown | 2011-05-09 |
| Series | Ice Age: A Mammoth Christmas | Sid | 2011-11-24 |
| Series | The Chew | Unknown | 2011-09-26 |
| Series | NerdHQ | Unknown | 2011-07-01 |
| Movie | Vanishing on 7th Street | Unknown | 2010 |
| Movie | Nickelodeon Mega Music Fest | Unknown | 2010 |
| Movie | The Cove: My Friend is... | Unknown | 2010-04-22 |
| Movie | Big Balls | Unknown | 2010 |
| Movie | Repo Men | Unknown | 2010-03-19 |
| Movie | The New America | Unknown | 2010 |
| Series | The Talk | Unknown | 2010-10-18 |
| Series | Conan | Unknown | 2010-11-08 |
| Movie | Blueprint for Accountability: Working the Dark Side | Unknown | 2009 |
| Movie | Righteous Kill - The Investigation: An In-Depth Look at 'Righteous Kill' | Unknown | 2009 |
| Movie | 2009 Alma Awards | Unknown | 2009-09-18 |
| Movie | The Ministers | Dante / Perfecto | 2009-10-16 |
| Movie | Rage | Unknown | 2009 |
| Series | The Electric Company | Unknown | 2009 |
| Movie | Ice Age: Dawn of the Dinosaurs | Unknown | 2009 |
| Series | Late Night with Jimmy Fallon | Unknown | 2009-03-02 |
| Movie | MTV Video Music Awards 2009 | Unknown | 2009-09-13 |
| Movie | Gamer | Unknown | 2009-09-04 |
| Movie | Ice Age: Dawn of the Dinosaurs | Unknown | 2009 |
| Series | Séries express | Unknown | 2008-04-17 |
| Movie | Surviving Sid | Unknown | 2008 |
| Movie | Miracle at St. Anna | Unknown | 2008 |
| Series | The Wendy Williams Show | Unknown | 2008-05-14 |
| Movie | Righteous Kill | Det. Simon Perez | 2008-09-12 |
| Series | D.L. Hughley Breaks the News | Unknown | 2008-10-25 |
| Movie | Macy's Thanksgiving Day Parade | Unknown | 2008-11-27 |
| Movie | The Happening | Unknown | 2008-06-13 |
| Movie | Paraiso Travel | Unknown | 2008 |
| Movie | Nothing Like the Holidays | Unknown | 2008 |
| Series | Chelsea Lately | Unknown | 2007-07-01 |
| Movie | Where God Left His Shoes | Frank Diaz | 2007-04-27 |
| Series | The Morning Show with Mike & Juliet | Unknown | 2007 |
| Series | Cinemassacre's Monster Madness | Unknown | 2007-10-01 |
| Movie | The Babysitters | Unknown | 2007 |
| Movie | Love in the Time of Cholera | Unknown | 2007-11-16 |
| Movie | ShowBusiness: The Road to Broadway | Unknown | 2007 |
| Movie | The Take | Unknown | 2007 |
| Series | The Kill Point | Unknown | 2007 |
| Movie | The 11th Annual Critics' Choice Awards | Unknown | 2006 |
| Movie | Mega Especiales: John Leguizamo | Unknown | 2006 |
| Movie | The Bondage | Unknown | 2006 |
| Movie | Lies & Alibis | Unknown | 2006-01-12 |
| Series | The Wendy Williams Experience | Himself - Guest | 2006-10-20 |
| Movie | Ice Age 2: The Meltdown | Sid | 2006-03-14 |
| Movie | Boffo! Tinseltown's Bombs and Blockbusters | Unknown | 2006-06-13 |
| Movie | The Groomsmen | Unknown | 2006 |
| Movie | Lost Historical Films on the Ice Age Period | Unknown | 2006 |
| Movie | Ice Age: The Meltdown | Unknown | 2006 |
| Movie | A.K.A. | Unknown | 2006 |
| Movie | Land of the Dead: A Day with the Living Dead | Himself | 2005-10-18 |
| Series | 20 to 1 | Unknown | 2005-09-29 |
| Movie | Carlito's Way: Brian De Palma on 'Carlito's Way' | Unknown | 2005 |
| Movie | Undead Again: The Making of 'Land of the Dead' | Unknown | 2005 |
| Movie | Land of the Dead: Bringing the Dead to Life | Himself | 2005-10-18 |
| Series | Made in Hollywood | Unknown | 2005-09-30 |
| Movie | Los 50 más bellos de People en Español | Unknown | 2005 |
| Series | My Name Is Earl | Unknown | 2005-09-20 |
| Movie | Sueño | Unknown | 2005 |
| Movie | The Honeymooners | Unknown | 2005 |
| Movie | Land of the Dead | Unknown | 2005 |
| Movie | Untitled David Diamond/David Weissman Project | Unknown | 2005 |
| Movie | Assault on Precinct 13 | Unknown | 2005 |
| Series | The Late Late Show with Craig Ferguson | Unknown | 2005-01-03 |
| Series | Martha | Unknown | 2005-09-01 |
| Series | American Dad! | Unknown | 2005-02-06 |
| Movie | Cronicas | Unknown | 2004 |
| Series | Tavis Smiley | Unknown | 2004-01-05 |
| Movie | Ceremonia de apertura del festival de cine de San Sebastián | Unknown | 2004 |
| Movie | Rayman 3: Hoodlum Havoc | Unknown | 2003 |
| Series | The Isaac Mizrahi Show | Unknown | 2003 |
| Movie | Undefeated | Unknown | 2003 |
| Movie | The 45th Annual Grammy Awards | Unknown | 2003 |
| Movie | The 57th Annual Tony Awards | Unknown | 2003-06-08 |
| Movie | Spun | Spider Mike | 2003-02-07 |
| Series | Jimmy Kimmel Live! | Unknown | 2003-01-26 |
| Series | Shootout | Unknown | 2003-10-12 |
| Movie | Pieces of Courage: In Search of My Cultural Heroes | Unknown | 2003 |
| Movie | Empire | Unknown | 2002-12-06 |
| Movie | AFI's 100 Years... 100 Passions: America's Greatest Love Stories | Unknown | 2002-06-11 |
| Movie | VH1 Big in 2002 Awards | Unknown | 2002-12-15 |
| Movie | Collateral Damage | Felix Ramirez | 2002-02-08 |
| Movie | Zig Zag | Unknown | 2002 |
| Movie | Point of Origin | Unknown | 2002 |
| Movie | The Bronze Screen: 100 Years of the Latino Image in American Cinema | Unknown | 2002 |
| Movie | De Superman à Spider-Man: L'aventure des super-héros | Unknown | 2002-06-01 |
| Movie | The 56th Annual Tony Awards | Unknown | 2002 |
| Movie | Scene Stealers | Unknown | 2002 |
| Movie | Ice Age | Unknown | 2002-03-15 |
| Movie | Sexaholix... A Love Story | Unknown | 2002 |
| Series | The Brothers Garcia | Unknown | 2001 |
| Movie | 2001 ALMA Awards | Unknown | 2001 |
| Movie | The Night Club of Your Dreams: The Making of 'Moulin Rouge' | Unknown | 2001 |
| Series | Dinner for Five | Unknown | 2001-07-07 |
| Movie | What's the Worst That Could Happen? | Unknown | 2001 |
| Series | Lugar Heights | Unknown | 2001 |
| Movie | Moulin Rouge! | Unknown | 2001-06-01 |
| Movie | Piñero | Unknown | 2001 |
| Series | Who Wants to Be a Millionaire | Unknown | 2001 |
| Movie | Nuyorican Dream | Unknown | 2000 |
| Movie | VH1/Vogue Fashion Awards | Unknown | 2000 |
| Movie | Open Sesame: The Making of 'Arabian Nights' | Himself | 2000-04-08 |
| Series | Dora the Explorer | Unknown | 2000-08-14 |
| Movie | My VH1 Music Awards | Unknown | 2000-11-30 |
| Movie | New York Magazine Awards Show 2000 | Unknown | 2000 |
| Movie | King of the Jungle | Unknown | 2000 |
| Series | Arabian Nights | Unknown | 2000 |
| Movie | Titan A.E. | Unknown | 2000 |
| Series | Loose Women | Unknown | 1999-09-06 |
| Series | The Late Late Show with Craig Kilborn | Unknown | 1999-03-31 |
| Movie | The Source: The Story of the Beats and the Beat Generation | Unknown | 1999-01-23 |
| Movie | Joe the King | Unknown | 1999 |
| Movie | The 51st Annual Primetime Emmy Awards | Unknown | 1999 |
| Movie | 1999 ALMA Awards | Unknown | 1999 |
| Movie | Summer of Sam | Unknown | 1999 |
| Movie | Doctor Dolittle | Unknown | 1998 |
| Series | Fox and Friends | Unknown | 1998-02-01 |
| Movie | The 52nd Annual Tony Awards | Unknown | 1998-06-07 |
| Movie | Frogs for Snakes | Unknown | 1998 |
| Movie | Freak | Unknown | 1998 |
| Movie | Kids Are Punny | Unknown | 1998 |
| Movie | Body Count | Chino | 1998-04-28 |
| Movie | The Pest | Unknown | 1997 |
| Series | The View | Unknown | 1997-08-11 |
| Movie | Spawn | Clown / Violator | 1997-08-01 |
| Movie | A Brother's Kiss | Unknown | 1997 |
| Movie | The Making of 'Super Mario Brothers' | Unknown | 1997 |
| Series | Showbiz Today | Unknown | 1996 |
| Movie | The 53rd Annual Golden Globe Awards | Unknown | 1996 |
| Movie | Executive Decision | Unknown | 1996 |
| Series | The Rosie O'Donnell Show | Unknown | 1996-06-10 |
| Movie | The Fan | Unknown | 1996-08-16 |
| Series | The Daily Show | Unknown | 1996-07-22 |
| Movie | Romeo + Juliet | Tybalt | 1996-11-01 |
| Series | House of Buggin' | Unknown | 1995 |
| Movie | To Wong Foo Thanks for Everything, Julie Newmar | Unknown | 1995 |
| Series | The Jon Stewart Show | Unknown | 1995 |
| Movie | A Pyromaniac's Love Story | Unknown | 1995 |
| Series | American Masters | Unknown | 1994 |
| Movie | The 8th Annual American Comedy Awards | Unknown | 1994 |
| Series | HBO First Look | Unknown | 1994-03-01 |
| Series | All That | Unknown | 1994-04-16 |
| Series | ER | Unknown | 1994-09-19 |
| Series | The Little Picture Show | Unknown | 1993-01-05 |
| Movie | Super Mario Bros. | Luigi Mario | 1993-05-28 |
| Series | Late Night with Conan O'Brien | Unknown | 1993-09-13 |
| Movie | Night Owl | Unknown | 1993 |
| Series | Late Show with David Letterman | Unknown | 1993-08-30 |
| Movie | Carlito's Way | Unknown | 1993 |
| Movie | Spic-O-Rama | Unknown | 1993 |
| Movie | Whispers in the Dark | Unknown | 1992 |
| Movie | Time Expired | Unknown | 1992 |
| Series | Getaway | Unknown | 1992-05-14 |
| Movie | Puerto Rican Mambo (Not a Musical) | Unknown | 1992 |
| Series | The Tonight Show with Jay Leno | Unknown | 1992-05-25 |
| Movie | Poison | Unknown | 1991-08-16 |
| Series | Charlie Rose | Unknown | 1991-09-30 |
| Movie | Out for Justice | Unknown | 1991 |
| Movie | Words in Your Face | Unknown | 1991 |
| Movie | N.Y.P.D. Mounted | Unknown | 1991 |
| Movie | Regarding Henry | Unknown | 1991-07-10 |
| Movie | Mambo Mouth | Unknown | 1991 |
| Movie | Hangin' with the Homeboys | Unknown | 1991 |
| Movie | That Burning Question | Unknown | 1990 |
| Movie | Madonna: The Immaculate Collection | Unknown | 1990 |
| Movie | Street Hunter | Unknown | 1990 |
| Movie | Die Hard 2 | Unknown | 1990-07-04 |
| Movie | Gentille alouette | Unknown | 1990 |
| Movie | Revenge | Ignacio | 1990-02-16 |
| Movie | Casualties of War | Unknown | 1989 |
| Movie | Mixed Blood | Unknown | 1984 |
| Movie | Madonna | Unknown | 1984 |
| Series | Miami Vice | Unknown | 1984-09-16 |
| Series | Today | Unknown | 1952-01-14 |